Thermal decontamination of biological effluents > GMP Decontamination autoclaves

GMP Decontamination autoclaves

Uncompromising GMP decontamination autoclaves, tailored to your daily challenges.

In the pharmaceutical, biotech, and cosmetic sectors, an autoclave is more than just equipment: it guarantees the integrity of your production cycles. At Actini Group, we design standard and custom decontamination solutions that transform regulatory constraints into powerful drivers of efficiency.

Capacity: starting at 500 liters
Sectors: Pharmaceutical, biotech, food-processing, and cosmetic laboratories and industries.

Gamme autoclaves de décontamination GMP Actini Group

Discover our GMP decontamination autoclaves

Steam vacuum

Ventilated

Why choose Actini Group’s expertise for your decontamination?

“Made in France” industrial excellence

Proud of our roots, we master the entire chain, from design to manufacturing, within our French workshops. This guarantees you an impeccable finish, immediate technical responsiveness, and equipment built to last.

A human-centric and usage-focused approach

We do more than just comply with standards (ISPE, GAMP 5, FDA). We design for the people who operate our machines every day:

Operator-Focused Ergonomics: We optimize loading heights and facilitate access to reduce physical strain.
Smart Maintenance: We offer the possibility to remote-mount the technical skid, allowing interventions without disturbing your cleanroom zones.
Energy Efficiency: We optimize cycles to drastically reduce your water and electricity consumption.

Systems adapted for Pharmaceutical, Biotech, Cosmetic, and Food Industries

Actini Group develops GMP decontamination autoclaves that integrate perfectly into the most demanding environments. In pharmaceutical, cosmetic, food, and biotech industries, they ensure controlled decontamination compliant with cGMP requirements for laboratories, production areas, or classified environments. Our industrial autoclaves provide reliable decontamination for equipment and effluents while meeting the safety and quality standards specific to each activity.

We think through every solution to adapt it to your processes, regulatory constraints, and level of requirement.

Two technologies, absolute precision

Steam-Vacuum Autoclave	Ventilated Autoclave
The expert for solids and contact surfaces	The specialist for sensitive loads
Ideal for decontaminating format parts, empty vials, textiles, and tools.	Designed for closed containers (filled vials, syringes, bags) requiring ultra-fine pressure control.
Decontamination via saturated steam (> 105°C)	Precise treatment and controlled cooling (> 90°C)

What do GMP or BPF mean?

GMP, or Good Manufacturing Practices (BPF in French), are much more than a regulatory framework. They are clear and rigorous rules that ensure a product is manufactured under perfectly controlled conditions, maintaining consistent and safe quality.

In practice, GMP cover every step: from raw materials to the final product. They emphasize hygiene, traceability, organization, procedural rigor, and continuous process control.

When a company is GMP certified, it means it adheres to strict standards recognized internationally—a crucial point in sensitive sectors like pharmaceuticals, biotechnology, cosmetics, or food.

BPF: safety first

An authorized manufacturer must ensure that a product is:

Suitable for its intended use
Compliant with validated specifications
Safe, effective, and of consistent quality

The goal is simple: never expose the user or patient to avoidable risk.

Preventing risks to ensure safety and quality

BPF primarily aim to prevent two major types of risks:

Cross-contamination (between products or via internal or external contaminants)
Errors or confusion, especially in labeling, identification, or handling of components

They therefore require strict organization, clear procedures, and impeccable hygiene practices at all levels of the company. In short, GMP are not just standards—they are concrete commitments to safety, quality, and trust.

Designed for performance and its users

Reliability & traceability: Our supervision system manages cycles according to your needs.
Ergonomic design: We optimize access, height, and loading to meet your HSE constraints.
Optimized cycles: We maximize energy performance.
Integrated pure steam production.
Strategic technical zones: Remote skid options facilitate maintenance.

Autoclave de stérilisation industriel Actini Group

Pharmaceutical GMP Autoclaves for Critical Environments

The pharmaceutical sector imposes critical standards for quality, safety, and traceability. To transform these regulatory constraints into performance drivers, Actini Group designs autoclaves specifically tailored to the most sensitive applications.

Each unit guarantees efficient and homogeneous decontamination of products, instruments, and materials, while strictly adhering to Good Manufacturing Practices (GMP) and international standards (FDA). Through robust design and total mastery of critical parameters (temperature, pressure), our autoclaves deliver absolute reliability for production environments that require full process validation.

Actini Group autoclaves: industrial performance and optimal laboratory integration

Our industrial autoclaves, while offering industrial-grade performance and proven robustness, can also be directly integrated into laboratory environments.

Actini Group autoclaves have several key advantages that make them reference solutions for laboratories:

They are specifically designed for the cGMP sector, with technologies adapted to pharmaceutical, biotechnological, and research environments.
Their capacity range is very wide (starting at 500 liters), allowing integration both in a laboratory and in a production line.
They offer various loading, door, and format options (sliding door, trolley, floor intake, etc.), facilitating installation and use in laboratory settings.
Automated cycle control, data traceability, and compliance with international standards ensure safety, reproducibility, and adherence to laboratory requirements.
Made in France, with full control over components and control interfaces, they guarantee manufacturing quality and technical support suited to the critical constraints of laboratories.

In summary, thanks to their robust design, integration flexibility, and high compliance, Actini Group autoclaves are particularly well suited for demanding laboratory environments.

SoBatch: Regain control of your data

Automation should not be a headache. We developed the SoBatch supervision system (compatible with Schneider or Siemens) to provide total transparency:

21 CFR Part 11 Compliance: It provides tamper-proof traceability for your audits.
Flexibility: You manage recipes and production cycles through an intuitive interface, even on equipment from other brands (Retrofit).
Global Vision: Centralize up to three units on a single interface.

SoBatch features

Access to settings
Process curves
Export of raw data and batch reports
Communication with your computer server
Management of up to 5 user levels
Centralized supervision of up to 3 devices
Audit Trail
Adjustment of analog inputs

Cycles programmed with SoBatch

Product decontamination cycle for solids and liquids
Compressed air filter sterilization cycle (SIP)
Compressed air filter WIT cycle
Leak test
Bowie-Dick cycle
Steam sampling

Technical data

Features

Capacity: 500 liters Max. pressure: 3 barg Max. temperature: 143°C

Types of charges

Liquids, solids, porous materials

Opening

Single or crosswise Horizontal or vertical sliding opening, or hinged

Loading

Carrier trolley Modular shelf baskets Automatic loading Full-height loading (optional)

Our various decontamination autoclaves

Steam-Vacuum Decontamination Autoclave

The saturated steam autoclave technology, also known as the conventional autoclave, is primarily used for sterilizing items that come into contact with the final product. It allows the treatment of various types of loads, such as open vials, unfilled syringes, stoppers and caps, as well as instruments and component parts.

Textiles, tools, equipment, and other solid items can also be sterilized at temperatures above 105 °C, ensuring effective and reliable sterilization.

Learn more about the steam-vacuum autoclave

Conception 3D d'un autoclave GMP sur mesure et intégration CAO dans une zone de production

Modélisation 3D d'un autoclave industriel Actini Group avec skid technique déporté pour optimisation de l'espace en salle propre

Ventilated Decontamination Autoclave

The ventilated autoclave technology is designed for the treatment of sensitive loads requiring precise pressure control. It is especially suited for sterilizing and cooling hermetically sealed containers.

This process allows the treatment of various types of loads, including sealed filled vials, filled syringes, ampoules, and solution bags, at temperatures above 90 °C.

Learn more about the ventilated autoclave

Custom capacities: From the lab to the factory

Whether you require a compact 500L volume for research or a industrial capacity, our ranges adapt to your available space.

Overview of our ranges

Parallelepipedic Range: Optimizes volume for bulky loads.
Cylindrical Range: Provides classic robustness for high-pressure applications.
Critical Options: We integrate BioSeal containment, built-in integrity tests, and slave steam generators to meet your specific needs.

Our parallelepiped range

Ref.	Width (mm)	Height (mm)	Depth (mm)	Volume (liters)
P815	800	1.500	2.000	2.400
P912	900	1.200	1.500	1.620
P916	900	1.600	2.000	2.880
P1010	1.000	1.000	1.000	1.000
P1012	1.000	1.200	2.000	2.400
P1419	1.400	1.900	2.000	5.320
P1520	1.500	2.000	2.000	6.000

Our range of cylindrical autoclaves

Ref.	Width (mm)	Height (mm)	Depth (mm)	Volume (liters)
C70	700	700	From 1.000 to 3.700	From 5.000 to 1.800
C80	800	800	From 1.000 to 3.700	From 640 to 2.350
C90	900	900	From 1.000 to 3.700	From 810 to 3.000
C100	1.000	1.000	From 1.000 to 5.000	From 1.000 to 5.000
C120	1.200	1.200	From 1.000 to 9.900	From 1.440 to 14.520
C1520	1.500	2.000	From 2.000 to 11.500	From 6.000 to 34.500

Options

Integrity test
Vapor sampling
Remote connection
Traceability of materials outside the process
Containment by BioSeal
Remote technical skid
Soft WinCC pro

Studies of utilities, connectivity, and scalability

Sizing of required utilities (electricity, steam, demineralized water, compressed air, N2, etc.) and planned drainage systems
Integration of a controlled steam generator if required
Sterilizing filtration of fluids with optional integrity testing in place
Option to relocate the technical skid for restricted environments

Would you like to learn more about our decontamination systems?

Contact us to benefit from the expertise of qualified professionals in the field of decontamination. Our experts will support you from the very beginning of your project by analysing your specific needs.